Philine brings nearly 20 years of experience in clinical cancer research to the table. She started her career in 1993 as a physiotherapist working at the Leiden University Medical Center. Her interest in clinical research and oncology led to an employment in 1997, at the Dutch Comprehensive Cancer Center West (CCC) were she was responsible for the project organization, coordination and execution of central and local data management of numerous clinical cancer trials. In 2008 she joined the Dutch Breast Cancer Research Group (BOOG) where she worked as a Clinical Study Manager to initiate, plan and manage clinical scientific breast cancer research. She was a driving force in developing and implementing improvement plans for organization processes, education programs, national quality framework for clinical research and database applications/systems. In addition, she co-founded an independent professional association (NVvOD) in which education and certification of the profession Data Manager was realized. In 2008-2009 Philine successfully studied innovative management at the University of Applied Sciences in Leiden covering main topics of Strategic, Change, Financial and Project management. Philine joined SMS-oncology in January 2012 as Director Operations and became COO a year later. She has successfully led the company and supervised the Clinical Operations group supporting all studies with her substantial experience in managing early and late phase oncology trials. With her strong entrepreneurial sense, can-do attitude and determination for excellence and client satisfaction Philine was promoted to CEO as of January 2016.